I tried using learning for Alt F4 to exit a window. Doesn't work. It learns Alt F4 but it sends it so many times that you end up exiting every application on my HTPC instead of closing the current window. I am guessing the learning method is at fault.

Workaround. Duplicate each device and use the duplicate for keys you only need for macros. It would be good if it worked without a workaround.